2015 · biomedical · Insights · Scientific

TDP: RNA metabolism and disease – ENCALS 2015 report


The fifth session of the ENCALS meeting focussed on the role of TDP-43 in ALS. The first talk during this session was given by myself (Jakub Scaber, MRC/MND Association Lady Edith Wolfson Fellow, University of Oxford). I was given the opportunity to present neuropathological data from the Oxford Brain Bank. Our study reaffirmed previous findings of…… Continue reading TDP: RNA metabolism and disease – ENCALS 2015 report

Insights · Scientific

Symposium report: Session 2A RNA processing and dysregulation


We were introduced to the topic by a very insightful plenary lecture by Laura Ranum, Professor of Molecular Genetics and Microbiology at the University of Florida. Professor Ranum started out by describing how the central dogma of molecular biology, namely that DNA makes RNA makes protein, had been modified during the last decade using examples…… Continue reading Symposium report: Session 2A RNA processing and dysregulation

Insights · Scientific

Session 2A – Neuronal Vulnerability in ALS/MND


While our understanding of ALS and its genetic background has been growing rapidly in recent years, we are still far away from understanding the selective neuronal death in ALS. The presentations in the first basic science session of this year’s symposium on ALS/MND provided new ideas on this fascinating subject. The session was opened by…… Continue reading Session 2A – Neuronal Vulnerability in ALS/MND