2015 · Clinical · Healthcare · Insights · Scientific

C9orf72 and novel therapeutics: report from ENCALS Friday 22nd May 2015 – Oral Session 3


Leonard Petruccelli commenced the session discussing mechanisms of toxicity and therapeutic approaches for C9FTD/ALS, beginning by highlighting the enormous advancement in the understanding of the genetics and neuropathology of FTD and ALS since 2006. The three proposed mechanism of C9orf72 mutations were presented; 1) a gain of toxicity as a result of RNA foci in…… Continue reading C9orf72 and novel therapeutics: report from ENCALS Friday 22nd May 2015 – Oral Session 3