2016 International Symposium - Dublin · biomedical · Insights · Scientific

Session 7C: Mouse Models


At the beginning of December 2016, hordes of research scientists and clinicians embarked upon Dublin, a.k.a. the ‘home of Guinness’, for the 27th International Symposium on ALS/MND. This was my second conference and the Dublin Convention Centre on the north bank of the river Liffey was a great setting. Session 7C focussed on mouse models…… Continue reading Session 7C: Mouse Models

2015 · 2015 International Symposium - Orlando · biomedical · Scientific

Theme 13: In vivo Experimental Models


When you think of Orlando you think vacations, theme parks and sunshine. However, for one weekend in December, ALS/MND researchers from around the globe gathered in America’s sunshine state for the 26th International Symposium on ALS/MND. This was the first Symposium I have attended during my PhD and I was excited to finally present all the research that the…… Continue reading Theme 13: In vivo Experimental Models

2015 · 2015 International Symposium - Orlando · biomedical · Insights · Scientific

Session 4A: Disease Models


Firstly, Dr Cathleen Lutz (The Jackson Laboratory, USA) discussed the range of current mouse models of MND and the potential for generating new models.  Lutz explored the many reasons why MND is a hard disease to model, and how the SOD1-G93A model has become the ‘workhorse’ for MND mouse modelling.  However, as subgroups and new…… Continue reading Session 4A: Disease Models

2015 · biomedical · Insights · Scientific

TDP: RNA metabolism and disease – ENCALS 2015 report


The fifth session of the ENCALS meeting focussed on the role of TDP-43 in ALS. The first talk during this session was given by myself (Jakub Scaber, MRC/MND Association Lady Edith Wolfson Fellow, University of Oxford). I was given the opportunity to present neuropathological data from the Oxford Brain Bank. Our study reaffirmed previous findings of…… Continue reading TDP: RNA metabolism and disease – ENCALS 2015 report