Discussion of respiratory management in caring for ALS patients is essential for their comfort, health and end-of-life decisions. This session covered a range of information from original diagnosis of respiratory failure, use of a diaphragm pacing system and experiences of termination or failure of ventilation from the perspectives of health professionals working in ALS centres…… Continue reading Respiratory Management in ALS – Session 8B from Brussels
Modelling a complex condition such as ALS in a laboratory is an understandably difficult concept, and it is perhaps unsurprising that we don’t yet have the perfect model. This session early on a Saturday morning looked at the different approaches to using cells in the lab to investigate ALS. The first speaker and one of…… Continue reading How can we model ALS in the lab? – Session 5A – In Vitro Modelling
The first talk in the GENETICS session was given by Roger Sher and demonstrated how the different genetic mouse backgrounds affect the survival of the human G93A SOD1 transgenic mice. In inbred lines, the B6 background extended life by 32 days whereas NOD, ALR and SJL backgrounds decreased the lifespan of the G93A SOD1 transgenic…… Continue reading ALS Symposium: Session 8A GENETICS
I just came back from the 23rd International Symposium on ALS/MND in Chicago. While recovering from my horrible jet lag (I live in Dublin, those 6h difference do not set well on me…) and the 14h trip, I got myself reviewing what I learned. First, I need to say that I only had half of the information…… Continue reading The Human Side
Fantastic 23rd International Symposium on ALS/MND! I am really excited to be here in Chicago! The Symposium kicked off with an amazing lecture from Dr Al-Chalabi giving an overview on the factors contributing to ALS, from nature to nurture, age and “luck”. I have never seen the factors contributing to ALS explained in a more…… Continue reading Fantastic 23rd International Symposium on ALS/MND!