2015 · biomedical · Insights · Scientific

TDP: RNA metabolism and disease – ENCALS 2015 report


The fifth session of the ENCALS meeting focussed on the role of TDP-43 in ALS. The first talk during this session was given by myself (Jakub Scaber, MRC/MND Association Lady Edith Wolfson Fellow, University of Oxford). I was given the opportunity to present neuropathological data from the Oxford Brain Bank. Our study reaffirmed previous findings of…… Continue reading TDP: RNA metabolism and disease – ENCALS 2015 report

2015 · Clinical · Healthcare · Insights

ENCALS 2015 Meeting, 21 – 23 May, Dublin: Highlights and insights of cognition session


This year Dublin was not only home to the annual ENCALS meeting 2015, but also to a referendum on gay marriage. One week after the meeting the buzz of the sessions is still with me.  This was an excellent event and the varied scientific sessions and posters helped to build my knowledge and understanding of…… Continue reading ENCALS 2015 Meeting, 21 – 23 May, Dublin: Highlights and insights of cognition session

2015 · Clinical · Healthcare · Insights · Scientific

C9orf72 and novel therapeutics: report from ENCALS Friday 22nd May 2015 – Oral Session 3


Leonard Petruccelli commenced the session discussing mechanisms of toxicity and therapeutic approaches for C9FTD/ALS, beginning by highlighting the enormous advancement in the understanding of the genetics and neuropathology of FTD and ALS since 2006. The three proposed mechanism of C9orf72 mutations were presented; 1) a gain of toxicity as a result of RNA foci in…… Continue reading C9orf72 and novel therapeutics: report from ENCALS Friday 22nd May 2015 – Oral Session 3

2015 · Clinical · Healthcare · Insights

ENCALS 2015 Meeting- Pioneering the Cognitive session


The biggest ALS European meeting was held this year in Dublin, Ireland. Due to unforeseen circumstances, the venue (i.e. country and city) had to be changed last minute from Milan, Italy. Nevertheless, Dublin as a city was riveting and impressive, which was further augmented by the electric atmosphere created by the same-sex marriage referendum that…… Continue reading ENCALS 2015 Meeting- Pioneering the Cognitive session

Insights · Scientific

ENCALS satellite meeting


December 4th, Brussels, Belgium Posted on behalf of Leonard van den Berg, chair of ENCALS and coordinator of ALS Centre Netherlands The ENCALS satellite meeting last Thursday December 4th was absolutely packed. Almost hundred mostly European researchers attended. ENCALS, the European Association for the Cure of ALS, currently has 28 member centres. They are listed…… Continue reading ENCALS satellite meeting